Tutorial

Translation between scRNA-seq and scATAC-seq paired data

scButterfly could make translation between scRNA-seq and scATAC-seq paired data using scButterfly model in scButterfly.butterfly.

• scButterfly-B usage

• scButterfly-T using augmentation with cell-type labels

• scButterfly-C using augmentation with MultiVI integrated labels

Extension usages of scButterfly framework

scButterfly provide a series of extension usage with preprocessing in scButterfly.data_processing and model in scButterfly.train_model (scRNA-seq ~ scATAC-seq), scButterfly.train_model_cite (scRNA-seq ~ ADT data) or scButterfly.train_model_perturb (single-cell perturbation responses data).

Translation between scRNA-seq and scATAC-seq unpaired data

• Unpaired data translation using scButterfly-T

Translation between scRNA-seq and scADT-seq paired data

• scButterfly-B usage

• scButterfly-T using augmentation with cell-type labels

• scButterfly-C using augmentation with totalVI integrated labels

Translation between single-cell perturbation responses data

• Perturbation responses prediction using scButterfly-T

Examples